top of page

2024

2024

Potential of piperine for neuroprotection in sepsis-associated encephalopathy

FERREIRA, FLÁVIA MONTEIRO; GOMES, STTEFANY VIANA; CARVALHO, LUANA CRISTINA FARIA; DE ALCANTARA, ANA CAROLINA; DA CRUZ CASTRO, MARIA LAURA; PERUCCI, LUIZA OLIVEIRA; PIO, SIRLAINE; TALVANI, ANDRÉ ; DE ABREU VIEIRA, PAULA MELO; CALSAVARA, ALLAN JEFFERSON CRUZ; Costa, Daniela Caldeira. Potential of piperine for neuroprotection in sepsis-associated encephalopathy. LIFE SCIENCES, p. 122353, 2023 DOI: https://doi.org/10.1016/j.lfs.2023.122353

2023
2022
2021
2020
2018
2017

2023

High-fat diet increases mortality and intensifies immunometabolic changes in septic mice

GOMES, STTEFANY VIANA; DIAS, BRUNA VIDAL; JÚNIOR, PEDRO ALVES MACHADO; PEREIRA, RENATA REBECA ; DE SOUZA, DÉBORA MARIA SOARES; BREGUEZ, GUSTAVO SILVEIRA; DE LIMA, WANDERSON GERALDO ; MAGALHÃES, CINTIA LOPES DE BRITO; CANGUSSÚ, SILVIA DANTAS; TALVANI, ANDRÉ ; QUEIROZ, KARINA BARBOSA; CALSAVARA, ALLAN JEFFERSON CRUZ; Costa, Daniela Caldeira. High-fat diet increases mortality and intensifies immunometabolic changes in septic mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2023. DOI: https://doi.org/10.1016/j.jnutbio.2023.109315

2022

Silymarin inhibits the lipogenic pathway and reduces worsening of non-alcoholic fatty liver disease (NAFLD) in mice

 

CARVALHO, LUANA CRISTINA FARIA ; FERREIRA, FLÁVIA MONTEIRO ; DIAS, BRUNA VIDAL ; AZEVEDO, DANIELA COUTO DE ; DE SOUZA, GUSTAVO HENRIQUE BIANCO ; MILAGRE, MATHEUS MARQUE ; DE LANA, MARTA ; VIEIRA, PAULA MELO DE ABREU ; CARNEIRO, CLÁUDIA MARTINS ; PAULA-GOMES, SÍLVIA DE ; CANGUSSU, SILVIA DANTAS ; Costa, Daniela Caldeira . Silymarin inhibits the lipogenic pathway and reduces worsening of non-alcoholic fatty liver disease (NAFLD) in mice. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, p. 1-15, 2022. DOI: https://doi.org/10.1080/13813455.2022.2138445.

Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice

COELHO, A.M.; QUEIROZ, I.F.; PERUCCI, L.O.; SOUZA, M.O.D.; LIMA, W.G.; TALVANI, A.; COSTA, D.C. Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice. Pharmaceutics 2022, 14, 1800. DOI: https://doi.org/10.3390/pharmaceutics14091800.

Temporal analysis of paracetamol-induced hepatotoxicity

 

COELHO, ALINE MEIRELES ; QUEIROZ, ISABELA FERREIRA ; Lima, Wanderson Geraldo ; TALVANI, ANDRÉ ; PERUCCI, LUIZA OLIVEIRA ; OLIVEIRA DE SOUZA, MELINA ; Costa, Daniela Caldeira . Temporal analysis of paracetamol-induced hepatotoxicity. DRUG AND CHEMICAL TOXICOLOGY, v. 22, p. 1-10, 2022. DOI: https://doi.org/10.1080/01480545.2022.2052891.

 

EPA/DHA and linseed oil have different effects on liver and adipose tissue in rats fed with a high-fat diet

 

BRUNA VIDAL ; GOMES, STTEFANY VIANA ; CASTRO, MARIA LAURA DA CRUZ ; CARVALHO, LUANA CRISTINA FARIA ; BREGUEZ, GUSTAVO SILVEIRA ; DE SOUZA, DÉBORA MARIA SOARES ; RAMOS, CAMILA DE OLIVEIRA ; SANT'ANA, MARCELLA RAMOS ; NAKANDAKARI, SUSANA CASTELO BRANCO RAMOS ; ARAUJO, CAROLINA MORAIS ; GRABE-GUIMARÃES, ANDREA ; TALVANI, ANDRÉ ; CARNEIRO, CLÁUDIA MARTINS ; CINTRA, DENNYS ESPER CORRÊA ; Costa, Daniela Caldeira . EPA/DHA and linseed oil have different effects on liver and adipose tissue in rats fed with a high-fat diet. PROSTAGLANDINS & OTHER LIPID MEDIATORS, v. 159, p. 106622, 2022. DOI: https://doi.org/10.1016/j.prostaglandins.2022.106622.

 
 

2021

Temporal effect of fructose supplementation at different concentrations on hepatic metabolism of Wistar rats

 

CARVALHO, LUANA CRISTINA FARIA; BRUNA, BRUNA VIDAL; GOMES, STTEFANY VIANA; CARNEIRO, CLÁUDIA MARTINS; COSTA,  DANIELA CALDEIRA . Temporal effect of fructose supplementation at different concentrations on hepatic metabolism of Wistar rats. Nutricion Hospitalaria, v. 28, p. 1-10, 2021. DOI: http://dx.doi.org/10.20960/nh.03691.

 

2020

Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats

Gomes, Sttefany Viana ; Dias, Bruna Vidal ; Pereira, Renata Rebeca ; De Pádua Lúcio, Karine ; DE Souza, Débora Maria Soares ; Talvani, André ; Brandão, Geraldo Célio ; Consenza, Gustavo Pereira ; De Queiroz, Karina Barbosa; Costa, Daniela Caldeira . Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats. Journal of Functional Foods, v. 66, p. 103780, 2020. DOI: https://doi.org/10.1016/j.jff.2020.103780.

 

Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in the Alloxan-induced Diabetic Rat Model

MIRANDA, L. M. ; AGOSTINI, L. ; Lima, W.G. ; CAMINI, F. C. ; COSTA, D.C. . Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in the Alloxan-induced Diabetic Rat Model. BIOMEDICAL AND ENVIRONMENTAL SCIENCES, v. 33, p. 690-700, 2020. DOI: http://dx.doi.org/10.3967/bes2020.090.

 

Silymarin: not just another antioxidant

Camini, Fernanda Caetano; Costa, Daniela Caldeira . Silymarin: not just another antioxidant. Journal of Basic and Clinical Physiology and Pharmacology, vol. 31, 2020. DOI: https://doi.org/10.1515/jbcpp-2019-0206

Baccharis trimera (carqueja) promotes gastroprotection on ethanol-induced acute gastric ulcer

Rabelo, Ana Carolina Silveira ; Camini, Fernanda Caetano; Bitencourt, Melissa Maia ; Lacerda, Kíssila ; De Lima, Wanderson Geraldo ; Costa, Daniela Caldeira . Baccharis trimera (carqueja) promotes gastroprotection on ethanol-induced acute gastric ulcer. Advances in Traditional Medicine, 2020.  DOI: https://doi.org/10.1007/s13596-020-00466-2.

 

2018

Anti-Inflammatory and Antioxidant Properties of Black Mulberry (Morus nigra L.) in a Model of LPS-Induced Sepsis

 

Lúcio, K. P.; Rabelo, A. C. S.; Araújo, C. M.; Brandão, G. C.; Souza, G. H. B.;  Silva, R. G.; Souza, D. M. S.; Talvani, A.; Bezerra, F. S.;  Calsavara, A. J. C.; Costa, D. C. Anti-Inflammatory and Antioxidant Properties of Black Mulberry (Morus nigra L.) in a Model of LPS-Induced Sepsis.  Oxidative Medicine and Cellular Longevity Volume 2018, Article ID 5048031. DOI: https://doi.org/10.1155/2018/5048031.

 

A review of biological and pharmacological activities of Baccharis trimera

Rabelo, A. C. S.; Costa, D. C . A review of biological and pharmacological activities of Baccharis trimera. Chemico-biological Interactions, v. 296, p. 65-75, 2018.

DOI: https://doi.org/10.1016/j.cbi.2018.09.002.

 

Oral formulation of DPP-4 inhibitor plus Quercetin improves metabolic homeostasis in type 1 diabetic rats

Miranda, P. H. A.; Lacerda, K. D. C.; Araújo, C. M.; Barichello, J. M.; Lima, W. G.; Costa, D. C.  Oral formulation of DPP-4 inhibitor plus Quercetina improves metabolic homeostasis in type 1 diabetic rats. Scientific Reports. Oct 17; 8(1):15310., 2018. DOI: http://dx.doi.org/10.1038/s41598-018-33727-x.

 

Baccharis trimera (carqueja) promotes gastroprotection on ethanol-induced acute gastric ulcer

Rabelo, Ana Carolina Silveira ; Camini, Fernanda Caetano; Bitencourt, Melissa Maia ; Lacerda, Kíssila ; De Lima, Wanderson Geraldo ; Costa, Daniela Caldeira . Baccharis trimera (carqueja) promotes gastroprotection on ethanol-induced acute gastric ulcer. Advances in Traditional Medicine, 2020.  DOI: https://doi.org/10.1007/s13596-020-00466-2.

 
 

2017

Aqueous extract of Baccharis trimera improves redox status and decreases the severity of alcoholic hepatotoxicity

 

Rabelo, A. C. S.; Araujo, G. R.; Lúcio, K. P.; Araujo, C. M.; Miranda, P. H. A.; Carneiro, A. C. A.; Ribeiro, E.; Lima, W.G.; Bianco, G. H.; Brandão, G. C.; Costa, D. C. Aqueous extract of Baccharis trimera improves redox status and decreases the severity of alcoholic hepatotoxicity. Revista Brasileira de Farmacognosia, 2017. DOI: http://dx.doi.org/10.1016/j.bjp.2017.09.003.

Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice

Bandeira, Ana Carla Balthar; Da Silva, Talita Prato; De Araujo, Glaucy Rodrigues; Araujo, Carolina Morais; Da Silva, Rafaella Cecília; Lima, Wanderson Geraldo; Bezerra, Frank Silva; Costa, Daniela Caldeira. Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice. Chemico-Biological Interactions (Print), v. 263, p. 7-17, 2017. DOI: https://doi.org/10.1016/j.cbi.2016.12.011.

Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in C57BL/6 mice

Bandeira, Ana Carla Balthar; Da Silva, Rafaella Cecília; Rossoni, Joamyr Victor; Figueiredo, Vivian Paulino; Talvani, André; Cangussú, Silvia Dantas; Bezerra, Frank Silva; Costa, Daniela Caldeira. Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in C57BL/6 mice. Bioorganic & Medicinal Chemistry (Print), v. 25, p. 1057-1065, 2017. DOI: https://doi.org/10.1016/j.bmc.2016.12.018.

 

The antioxidant and anti-inflammatory properties of lycopene in mice lungs exposed to cigarette smoke

Campos, K.K.D.; Araújo, G.R.; Martins, T.L.; Bandeira, A.C.B.; Costa, G.P.; Talvani, A.; Garcia, C.C.M.; Oliveira, L.A.; Costa, D.C.; Bezerra, F.S. The antioxidant and anti-inflammatory properties of lycopene in mice lungs exposed to cigarette smoke. Journal of Nutritional Biochemistry, v. 48, p. 9-20, 2017. DOI: https://doi.org/10.1016/j.jnutbio.2017.06.004.

 

Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47phox phosphorylation of NADPH oxidase in SK Hep-1 cells

De Araujo, G. R.; Rabelo, A. C. S.; Meira, J. S.; Rossoni-Junior, J. V.; Castro-Borges, W. D.; Guerra-Sa, R.; Batista, M. A.; Silveira-Lemos, D. D.; Souza, G. H. B. D.; Brandao, G. C.; Chaves, M. M.; Costa, D. C. Baccharis trimera inhibits reactive oxygen species production through PKC and down-regulation p47phox phosphorylation of NADPH oxidase in SK Hep-1 cells. Experimental Biology and Medicine (Maywood, N.J.: Print), v. 242, p. 333-343, 2017. DOI: https://doi.org/10.1177/1535370216672749.

 
bottom of page